교수

• · 2014, Ph.D. in Physics, Korea Advanced Institute of Science and Technology (KAIST)
• · 2006, B.S. in Mathematics (Double major Physics), KAIST

• · 2022–present Assistant professor, Seoul National University
• · 2021–2021 Research professor, Korea Advanced Institute of Science and Technology
• · 2017-2019 Marie Sklodowska-Curie fellow, Delft University of Technology
• · 2016–2021 Postdoctoral researcher, KAVLI Institute, Delft University of Technology
• · 2014–2015 Postdoctoral researcher, Korea Advanced Institute of Science and Technology

HS-AFM, 단분자 형광기법과 자기 집게 법등의 단분자 기법을 이용하여, 단백질의 구조 동역학을 초고해상도 (< 1 nm), 초고시간분해능 (~ 10 ms) 으로 관찰합니다. 염색체 구성과 염색체와 연관된 생물학적인 현상에 관여하는 단백질들과 생체막 단백질의 구조 동역학을 연구합니다.

1. Je-Kyung Ryu, Sang-Hyun Rah, Richard Janissen, Jacob W. Karppenmakers, and Cees Dekker, “Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating process”, Nucleic Acids Research (Impact factor: 16.971), gkab1268, (2021).
2. Je-Kyung Ryu, Celine Bouchoux, Hon Wing Liu, Eugene Kim, Masashi Minamino, Ralph de Groot, Allard Katan, Andrea Bonato, Davide Marenduzzo, Davide Michieletto, Frank Uhlmann, and Cees Dekker, “Phase separation induced by cohesin SMC complexes”, Science Advances, 7(7), eabe5905 (2021).
3. Je-Kyung Ryu, Allard Katan, Eli van der Sluis, Thomas Wisse, Jaco van der Torre, Ralph de Groot, Christian Haering, and Cees Dekker, “The condensin holocomplex cycles dynamically between open and collapsed states”, Nature Structural Molecular Biology, 27(12), 1134-1141 (2020).
4. Je-Kyung Ryu, Soo Jin Kim, Sang-Hyun Rah, Ji In Kang, Hi Eun Jung, Heung-Kyu Lee, Jie-Oh Lee, Beom Seok Park, Tae-Young Yoon, and Ho Min Kim, “Reconstruction of LPS transfer cascade reveals structural determinants within LBP, CD14 and TLR4-MD2 for efficient LPS recognition and transfer”, Immunity (Impact factor: 31.745), 46(1), 38-50 (2017).
5. Je-Kyung Ryu, Duyoung Min, Sang-Hyun Rah, Soo Jin Kim, Yongsoo Park, Haesoo Kim, Changbong Hyeon, Ho Min Kim, Reinhard Jahn & Tae-Young Yoon “Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover”, Science, 347(6229), 1485-1489 (2015).