교수

Department of Physics & Astronomy
박혜윤
박혜윤부교수
Associate ProfessorPark, Hye Yoon
연구실 : 56-431 , 02-880-4133
http://neurobiophysics.snu.ac.kr (신경생물물리 실험실)

학력

  • · 2007 Ph.D. in Applied Physics, Cornell University
  • · 2002 M.S. in Applied Physics, Cornell University
  • · 1999 B.S. in Physics, Seoul National University

주요경력

  • · 2014-present Assistant Professor, Associate Professor, Seoul National University
  • · 2008-2014 Research Fellow, Albert Einstein College of Medicine
  • · 2007-2008 Postdoc, Cornell University

연구내용

우리 연구실은 유전자 발현이 살아있는 동물의 신경망 안에서 어떻게 조절되는지 연구하기 위한 새로운 생물물리학 기술들을 개발하고 있습니다. 광학, 멀티 모달 이미징, 미세 유체 공학, 생화학, 유전 공학 및 정량적 단일 분자 분석을 결합한 다각적인 접근법을 기반으로 아래의 주제들에 관해 연구하고 있습니다.
• Development of non-invasive imaging techniques to probe gene expression in live animals
• Dynamics of transcription and localization of single RNA in the neural network of the brain
• Dynamic remodeling of ribonucleoprotein (RNP) complexes during the life cycle of RNA

최근 5년간 주요논문

  1. Das, S., Moon, H. C., Singer, R. H., and Park, H. Y. (2018). A Transgenic Mouse for Imaging Activity-Dependent Dynamics of Endogenous Arc mRNA in Live Neurons. Science Advances 4, eaar3448.
  2. Song, M. S., Moon, H. C., Jeon, J.-H., and Park, H. Y. (2018). Neuronal Messenger Ribonucleoprotein Transport Follows an Aging Lévy Walk. Nature Communications 9, 344.
  3. Lee, B. H. and Park, H. Y. (2018). HybTrack: A Hybrid Single Particle Tracking Software Using Manual and Automatic Detection of Dim Signals. Scientific Reports 8, 212.
  4. Buxbaum, A. R., Yoon, Y. J., Singer, R. H, and Park, H. Y. (2015). Single-Molecule Insights into mRNA Dynamics in Neurons. Trends in Cell Biology 25, 468.
  5. Park, H. Y., Lim, H., Yoon, Y. J., Follenzi, A., Nwokafor, C., Lopez-Jones, M., Meng, X., and Singer, R. H. (2014). Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse. Science 343, 422.