Professors

• · 2007 Ph.D. in Applied Physics, Cornell University
• · 2002 M.S. in Applied Physics, Cornell University
• · 1999 B.S. in Physics, Seoul National University

• · 2014-present Assistant Professor, Associate Professor, Seoul National University
• · 2008-2014 Research Fellow, Albert Einstein College of Medicine
• · 2007-2008 Postdoc, Cornell University

My laboratory develops new biomedical tools to study how gene expression is regulated at the RNA level in the neural network of live animals. Our research is based on a multifaceted systems approach combining optics, multi-modal imaging, microfluidics, biochemistry, genetic engineering, and quantitative single-molecule analysis. Our current projects cover the following topics.
• Development of non-invasive imaging techniques to probe gene expression in live animals
• Dynamics of transcription and localization of single RNA in the neural network of the brain
• Dynamic remodeling of ribonucleoprotein (RNP) complexes during the life cycle of RNA

1. Das, S., Moon, H. C., Singer, R. H., and Park, H. Y. (2018). A Transgenic Mouse for Imaging Activity-Dependent Dynamics of Endogenous Arc mRNA in Live Neurons. Science Advances 4, eaar3448.
2. Song, M. S., Moon, H. C., Jeon, J.-H., and Park, H. Y. (2018). Neuronal Messenger Ribonucleoprotein Transport Follows an Aging Lévy Walk. Nature Communications 9, 344.
3. Lee, B. H. and Park, H. Y. (2018). HybTrack: A Hybrid Single Particle Tracking Software Using Manual and Automatic Detection of Dim Signals. Scientific Reports 8, 212.
4. Buxbaum, A. R., Yoon, Y. J., Singer, R. H, and Park, H. Y. (2015). Single-Molecule Insights into mRNA Dynamics in Neurons. Trends in Cell Biology 25, 468.
5. Park, H. Y., Lim, H., Yoon, Y. J., Follenzi, A., Nwokafor, C., Lopez-Jones, M., Meng, X., and Singer, R. H. (2014). Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse. Science 343, 422.